02-2258-7448

    주요연구분야 : 간암 발생에서 RNA 교정 효소에 의한 miRNA 교정 및 기능 연구

 Publication

​​​

• MicroRNA-495-3p functions as a tumor suppressor by regulating multiple epigenetic modifiers in gastric carcinogenesis.

       Eun JW*, Kim HS*, Shen Q, Yang HD, Kim SY, Yoon JH, Park WS, Lee JY, Nam SW.

       J Pathol. 2018 Jan;244(1):107-119. doi: 10.1002/path.4994. *Equally contributed

       IF:​ 5.942

​​

• Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis.

       Kim HS, Shen Q, Nam SW.

       J Korean Med Sci. 2015 Oct;30(10):1375-80. doi: 10.3346/jkms.2015.30.10.1375.     

       IF: 1.716 

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• MicroRNA-31 functions as a tumor suppressor by regulating cell cycle and epithelial-mesenchymal transition regulatory proteins in liver cancer.

       Kim HS*, Lee KS*, Bae HJ, Eun JW, Shen Q, Park SJ, Shin WC, Yang HD, Park M, Park WS, Kang YK,

       Nam SW.

       Oncotarget. 2015 Apr 10;6(10):8089-102. *Equally contributed

       IF: 5.168​​​

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• Oncogenic potential of CK2α and its regulatory role in EGF-induced HDAC2expression in human liver cancer.

       Kim HS, Chang YG, Bae HJ, Eun JW, Shen Q, Park SJ, Shin WC, Lee EK, Park S, Ahn YM, Park WS, Lee JY,

       Nam SW.

       FEBS J. 2014 Feb;281(3):851-61.

       IF: 4.739

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 Patents

•  2014 간암의 진단 및 치료를 위한 마이크로 RNA-31의 용도 (10-2014-0181326)

 Awards

• 2016. 02. 11 BK21사업단 우수 논문상 가톨릭대학교 BK21생명의과학사업단

 

    in Ph.D. Course

    02-2258-7448

    주요연구분야 : 신규한 긴가닥 비번역 RNA (novel lncRNA)에 의한 간암발생기전연구

                              Iso-miRNA의 신규 타겟 유전자에 의한 간암발생기전연구

                              선택적 3`폴리아데틸화 (Alternative polyadenylation, APA) 에 의한 간암발생기전연구

Publication

• Pathogenic diversity of RNA variants and RNA variation-associated factors in cancer development.

       Yang HD, Nam SW

       Exp Mol Med. 2020 Apr (accepted)​, review

       IF: 4.743

 

• HDAC6 Suppresses Let-7i-5p to Elicit TSP1/CD47-mediated Anti-tumorigenesis and Phagocytosis of Hepatocellular Carcinoma.

       Yang HD, Kim HS, Kim SY, Na MJ, Yang G, Eun JW, Wang HJ, Cheong JY, Park WS, Nam SW.

       Hepatology. 2019 Oct;70(4):1262-1279. doi: 10.1002/hep.30657.

       IF: 14.971

​

• T-cell immune regulator 1 enhances metastasis in hepatocellular carcinoma

       Yang HD*, Eun JW*, Lee KB*, Shen Q, Kim HS, Kim SY, Seo DW, Park WS, Lee JY, Nam SW.

       Exp Mol Med. 2018 Jan 5;50(1):e420. doi: 10.1038/emm.2017.166. *Equally contributed

       IF: 4.743

​​

• Oncogenic potential of histone-variant H2A.Z.1 and its regulatory role in cell cycle and epithelial-mesenchymal transition in liver cancer.

       Yang HD*, Kim PJ*, Eun JW, Shen Q, Kim HS, Shin WC, Ahn YM, Park WS, Lee JY, Nam SW.

       Oncotarget. 2016 Mar 8;7(10):11412-23. doi: 10.18632/oncotarget.7194. *Equally contributed

       IF: 5.168

 

     Patents

• 2019 간암의 예방 또는 치료용 조성물 (국내특허 출원 10-2019-0041829)

• 2019 간암의 재발 및 예후 예측용 TCIRG1 마커 및 이의 용도 (국내특허 등록 10-2042332-0000)

• 2018 신규한 간암 치료제 타겟으로서 H2AZ.1의 용도 (국내특허 등록10-1927577-0000)

• 2017 Use of H2A.Z.1 as a hepatocellular carcinoma biomarker (미국특허 출원15/408987)

    in Ph.D. Course

    02-2258-7448

    주요연구분야 : 간암 특이적으로 과발현되는 lncRNA의 기능 규명 연구

Publication

• Characteristic molecular signature of pericardial effucion identifies malignant cancer in pericardial disorder patients

       Kim SY, Eun JW, Kim HS, Yang HD, Na MJ, Ahn YM, Jung HO, Nam SW.

       Molecular & Cellular Toxicology. 2020.

       IF: 1.830

 

    in Ph.D. Course

    02-2258-7448

    주요연구분야 : DNA Mismatch repair protein에 의한 간암발생기전 연구

Publication

• ​

   in M.S Course

   02-2258-7448